Brain tumors
Biodistribution of temozolomide (Principal Investigator: dr. M. van Linde)
The effect of dexamethasone on the biodistribution of [3-N-11C-methyl]temozolomide in glioblastoma multiforme patients.
HGG-TCP (Principal Investigator: dr. M. van Linde)
Pilot study on the determination of tumor concentrations of protein kinase inhibitors in patients with newly diagnosed high-grade glioma.
ROAR (BRF117019) (Principal Investigator: dr. M. van Linde)
A Phase II, Open-label, Study in Subjects with BRAF V600EMutated Rare Cancers with Several Histologies to Investigate the Clinical Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib.
M13-813 (Principal Investigator: dr. M. van Linde)
A Randomized, Placebo Controlled Phase 2b/3 Study of ABT-414 with Concurrent Chemoradiation and Adjuvant Temozolomide in Subjects with Newly Diagnosed Glioblastoma (GBM) with Epidermal Growth factor Receptor (EGFR) Amplification.
MACIST (Principal Investigator: dr. M. van Linde)
Phase Ib study of Metformin and Chloroquine in IDH1/2-mutated Solid Tumors (MACIST).