Molecular diagnosis and genomics-based staging of head and neck cancer
Clinical problems in the treatment of head and neck cancer patients are locoregional recurrences (LR), delayed lymph node metastases, distant metastases (DM) and second primary tumors Genetic assays are run on HNSCC to investigate whether a certain profile is associated with the development of metastases. We also evaluate a molecular diagnostic approach that allows identification of patients with locoregional minimal residual cancer, patients with unresected high-risk precursor lesions and patients free of both, to guide postoperative clinical management.
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