Research line 1
Molecular diagnosis and therapy of cancer and precursor lesions Head and Neck Cancer Research VUmc Amsterdam
This research line focuses on genetic characterization of head and neck carcinogenesis. At the clinical level precursor lesions are studied to identify the events that predict progression to cancer. Concerning cancer, genetic analyses have been developed to explain and predict cancer recurrences, i.e. minimal residual cancer cells, second field cancers and metastatic disease.
These are the four projects:
- Head and neck cancer predisposition
- Molecular diagnosis and genomics-based staging of head and neck cancer
- Genes causing head and neck cancer
- Detection and treatment of oral preneoplasia
Personnel Head and Neck VUmc Amsterdam
Prof. Ruud H. Brakenhoff, PhD, MD, projectleader
Dr. Boudewijn JM Braakhuis, PhD, projectleader
Prof. C.René Leemans, PhD, MD, projectleader
Marijke Buijze, BSc, technician
Sanne R de Kemp, MSc, PhD-student
A. Peggy Graveland, MD, PhD-student
Géke B Flach, MD, PhD-student
Marlon van der Plas, MSc, PhD-student
Arjen Brink, MSc, technician
Birgith Witte, PhD, methodologist
Michelle M. Rietbergen, MD, PhD-student
Marijke Stigter-van Walsum, BSc, technician
Wessel van Wieringen, PhD biostatistician
Vicky de Boer, MSc, PhD-student
Anne M. van Harten, MSc, PhD-student
Jantine E. Bakema, PhD, projectleader
Collaborations
Vumc Amsterdam
Prof. Elisabeth Bloemena, Department of Pathology, MD, PhD
Dr. Jacqueline Cloos, Department of Pediatrics, PhD
Prof. Hans Joenje, Department of Human Genetics, PhD
Prof. Peter JF Snijders, Department of Pathology, MD, PhD
Dr. Bauke Ylstra, Microarray Core Facility, PhD
Prof. Isaac van der Waal, Department of Oral and Maxillofacial Surgery, MD, PhD
Within a framework
EUFAR
Airforce (CTMM)
National and international
Prof. R. Baatenburg- de Jong, MD, PhD, Erasmus University, Rotterdam, NL
Prof. P.J. Bradley, MD, PhD, University of Nottingham, Nottingham, UK
Prof. A. Heck, PhD, and Dr M. Slijper, PhD, University of Utrecht, NL
Prof. M. Partridge, MD, PhD, King's College London, UK
Prof. P. Slootweg, MD, PhD, and dr Robert Takes, MD, PhD, University of Nijmegen, NL
Prof. R.J.J. van Es, MD, PhD, University of Utrecht, NL
Dr. F. Leusink, PhD, University of Utrecht, NL